Behcet's disease: infectious aetiology, new autoantigens, and HLA-B51
نویسندگان
چکیده
منابع مشابه
hla-b51 in behçet’s disease
there is some data in the literature on the association of hla-b5 and some manifestations of behçet's disease (bd), especially ocular lesions. we studied 433 patients to see if there was any relationship between b51 and the manifestations of the disease. clinical manifestations of bd were compared in patients having hla-b51 (155 patients) and those lacking hla-b51 (278 patients). oral aphthosis...
متن کاملPrimary association of HLA-B51 with Behçet's disease in Ireland.
AIMS/BACKGROUND While a primary association of HLA-B51 with Behçet's disease (BD) in Japanese and Mediterranean patients supports an immunogenetic predisposition, this link is unclear in north western Europe. This study assessed HLA associations with BD, and HLA-B51 with certain clinical characteristics, in the Republic of Ireland, which has an ethnically homogeneous population. METHODS HLA-A...
متن کاملAssociation of MICA polymorphism with HLA-B51 and disease severity in Korean patients with Behcet's disease.
The HLA-B51 allele is known to be associated with Behcet's disease (BD) in many ethnic group. However, it has not yet been clarified whether the HLA-B51 gene itself is the pathogenic gene related to BD or whether it is some other gene in linkage disequlibrium with HLA-B51. Recently, the Triplet repeat (GCT/AGC) polymorphism in transmembrane region of the MHC class I chain-related A (MICA) gene ...
متن کاملSymptom management in Behcets disease.
OBJECTIVE To determine the symptoms experienced by patients diagnosed with Behcet's Disease and how they cope with them. METHODS The qualitative study was conducted from September 2013 to March 2014 at Ege University Medical Faculty Hospital, Turkey, comprising patients having all symptoms of Behcet's Disease. Data was collected through semi-structured focus-group interview form. The findings...
متن کاملHLA-B51 subtypes in Turkish patients with Behçet's disease and their correlation with clinical manifestations.
Behçet's disease (BD) is a multisystemic inflammatory disease believed to be triggered by microbial or environmental factors on a genetic platform. Clinically, it may have an impact on many body systems, including the mucocutaneous, ocular, articular, vascular, and neurological systems. In this study, we aimed to determine the HLA-B51 subtypes and their correlations with the clinical findings o...
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ژورنال
عنوان ژورنال: Annals of the Rheumatic Diseases
سال: 2001
ISSN: 0003-4967
DOI: 10.1136/ard.60.11.996